(1 reference)-
- 抗原 See all MAP3K2 抗体
- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
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抗原表位
- AA 606-619, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP3K2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 2(MAP3K2) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- SADELLRHMF VHYH
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 2(MAP3K2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: mitogen-activated protein kinase kinase kinase 2
Protein Name: Mitogen-activated protein kinase kinase kinase 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MEKK2(606-619aa SADELLRHMFVHYH), different from the related rat and mouse sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product MAP3K2 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibody
MAP3K2 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibodyMAP3K2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 357-619) antibodyMAP3K2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 111-200) antibodyMAP3K2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 14-43), (N-Term) antibodyMAP3K2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34479 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibodyMAP3K2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 146-195) antibodyMAP3K2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 1-180) antibodyMAP3K2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling." in: Cancer letters, Vol. 355, Issue 2, pp. 288-96, (2014) (PubMed).
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: "The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling." in: Cancer letters, Vol. 355, Issue 2, pp. 288-96, (2014) (PubMed).
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- 抗原
- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
- 别名
- MAP3K2 (MAP3K2 产品)
- 别名
- Mekk2 antibody, MEKK2 antibody, MEKK2B antibody, 9630061B06Rik antibody, AI585793 antibody, Mekk2b antibody, mitogen activated protein kinase kinase kinase 2 antibody, mitogen-activated protein kinase kinase kinase 2 antibody, Map3k2 antibody, MAP3K2 antibody
- 背景
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MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase(MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.
Synonyms: M3K2_HUMAN antibody|Map3k2 antibody|MAPK/ERK kinase kinase 2 antibody|MEK kinase 2 antibody|MEKK 2 antibody|MEKK2b antibody|Mitogen activated protein kinase kinase kinase 2 antibody|Mitogen-activated protein kinase kinase kinase 2 antibody - UniProt
- Q9Y2U5
- 途径
- MAPK Pathway
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