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MAP3K2 抗体

There are 2+ publications for this product available. The 小鼠 单克隆 anti-MAP3K2 antibody is suitable to detect MAP3K2 in samples from 人. It has been validated for ELISA 和 ICC.
产品编号 ABIN969272
发货至: 中国
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Quick Overview for MAP3K2 抗体 (ABIN969272)

抗原

See all MAP3K2 抗体
MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

适用

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宿主

  • 50
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小鼠

克隆类型

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单克隆

标记

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This MAP3K2 antibody is un-conjugated

应用范围

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ELISA, Immunocytochemistry (ICC)

克隆位点

4B4
  • 原理

    MAP3K2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human MAP3K2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

    Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

  • 抗原

    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

    别名

    MAP3K2

    背景

    The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

    分子量

    70 kDa

    UniProt

    Q9Y2U5

    途径

    MAPK Pathway
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