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MAP2K6 抗体 (N-Term)

MAP2K6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042996
发货至: 中国
  • 抗原 See all MAP2K6 抗体
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    抗原表位
    • 19
    • 15
    • 11
    • 9
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
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    AA 7-23, N-Term
    适用
    • 74
    • 63
    • 39
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 88
    • 6
    • 2
    克隆类型
    • 90
    • 6
    多克隆
    标记
    • 47
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAP2K6 antibody is un-conjugated
    应用范围
    • 83
    • 41
    • 27
    • 27
    • 16
    • 14
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 6(MAP2K6) detection. Tested with WB in Human,Mouse,Rat.
    序列
    KKRNPGLKIP KEAFEQP
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 6(MAP2K6) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: mitogen-activated protein kinase kinase 6
    Protein Name: Dual specificity mitogen-activated protein kinase kinase 6
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human MEK6(7-23aa KKRNPGLKIPKEAFEQP), identical to the related mouse sequence and different from the related rat sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product MAP2K6 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for MAP2K6 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    别名
    MAP2K6 (MAP2K6 产品)
    别名
    MAPKK6 antibody, MEK6 antibody, MKK6 antibody, PRKMK6 antibody, SAPKK-3 antibody, SAPKK3 antibody, Mkk6 antibody, Prkmk6 antibody, MKK3 antibody, map2k3 antibody, zMKK3 antibody, map2k6 antibody, mitogen-activated protein kinase kinase 6 antibody, mitogen-activated protein kinase kinase 6 L homeolog antibody, MAP2K6 antibody, Map2k6 antibody, map2k6 antibody, map2k6.L antibody
    背景
    MAP2K6(Mitogen-activated protein kinase kinase 6), also known as MAP kinase kinase 6(MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein(MAP) kinase kinase. Han et al.(1996) described experiments addressing the function of MKK6 in intracellular signaling pathways leading toward activation of p38 MAPK. Mukherjee et al.(2006) found that the Yersinia YopJ virulence factor acted as an acetyltransferase, using coenzyme A to modify critical ser and thr residues in the MAP2K6 activation loop, thereby blocking phosphorylation and kinase activation. They proposed that ser and/or thr acetylation by a bacterial effector may be a mechanism that occurs in other signaling pathways.

    Synonyms: Dual specificity mitogen activated protein kinase kinase 6 antibody|Dual specificity mitogen-activated protein kinase kinase 6 antibody|EC 2.7.12.2 antibody|MAP kinase kinase 6 antibody|MAP2K6 antibody|MAPK/ERK kinase 6 antibody|MAPKK 6 antibody|MAPKK6 antibody|MEK 6 antibody|MEK6 antibody|Mitogen Activated Protein Kinase Kinase 6 antibody|MKK 6 antibody|MKK6 antibody|MP2K6_HUMAN antibody|PRKMK6 antibody|Protein kinase mitogen activated kinase 6 antibody|protein kinase, mitogen-activated, kinase 6(MAP kinase kinase 6) antibody|SAPK kinase 3 antibody|SAPKK-3 antibody|SAPKK3 antibody|SKK3 antibody|Stress-activated protein kinase kinase 3 antibody
    UniProt
    P52564
    途径
    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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