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IL-1 beta 抗体 (C-Term)

Name: IL-1 beta 抗体 (C-Term)
SKU: ABIN3042625
Availability: OutOfStock

This anti-IL-1 beta antibody is a 兔多克隆 antibody detecting IL-1 beta in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Anti-IL1 beta antibody, Western blotting Lane 1: Recombinant Human IL-1 beta Protein 20ng Lane 2: Recombinant Human IL-1 beta Protein 10ng (IL-1 beta 抗体 (C-Term))

1 image

(5 references)

产品编号 ABIN3042625

发货至: 中国

Quick Overview for IL-1 beta 抗体 (C-Term) (ABIN3042625)

抗原

See all IL-1 beta (IL1B) 抗体

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

适用

人

宿主

兔

克隆类型

多克隆

标记

This IL-1 beta antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product IL1B Primary Antibody

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AA 249-269, C-Term

原理

Anti-IL1 beta/IL1B Antibody Picoband®

序列

FLGGTKGGQD ITDFTMQFVS S

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-IL1 beta/IL1B Antibody (ABIN3042625). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human IL-1 beta.

亚型

IgG
anti-Interleukin 1, beta (IL1B) (AA 101-200) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) antibody
IL1B 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A6 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 161-269) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 170-269) antibody
IL1B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A8 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F12D5 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-266) antibody
IL1B 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-269) antibody
IL1B 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 148-174) antibody
IL1B 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21917 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 148-174) antibody
IL1B 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Webb, A. C., Collins, K. L., Auron, P. E., Eddy, R. L., Nakai, H., Byers, M. G., Haley, L. L., Henry, W. M., Shows, T. B. Interleukin-1 gene (IL1) assigned to long arm of human chromosome 2. Lymphokine Res. 5: 77-85, 1986. 2. Auron, P. E., Webb, A. C., Rosenwasser, L. J., Mucci, S. F., Rich, A., Wolff, S. M., Dinarello, C. A. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Nat. Acad. Sci. 81: 7907-7911, 1984. 3. Dinarello, C. A. An update on human interleukin-1: from molecular biology to clinical relevance. J. Clin. Immun. 5: 287-297, 1985.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Bi, Zeng, Zhao, Wei, Yu, Wang, Yu, Cao, Shan, Wei: "miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα." in: Molecular therapy. Nucleic acids, Vol. 5, Issue 9, pp. e368, (2016) (PubMed).

Wang, Gong, Chen, Xiong, Zhou, Huang, Kong: "NLRP3 inflammasome sequential changes in Staphylococcus aureus-induced mouse model of acute rhinosinusitis." in: International journal of molecular sciences, Vol. 15, Issue 9, pp. 15806-20, (2015) (PubMed).

Li, Chen, Zhang, Song, Mu: "Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats." in: Neural regeneration research, Vol. 7, Issue 5, pp. 325-31, (2015) (PubMed).

Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

Yao, Peng, Peng, Tan, Wu, Wu, Chen, Li, Li, Zhu: "Effects of extract of Buddleja officinalis on partial inflammation of lacrimal gland in castrated rabbits with dry eye." in: International journal of ophthalmology, Vol. 3, Issue 2, pp. 114-9, (2012) (PubMed).
抗原

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

别名

IL1B

背景

Synonyms: Interleukin-1 beta,IL-1 beta,Catabolin,IL1B,IL1F2,
Tissue Specificity: Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.
Background: Interleukin-1 beta (IL-1beta) also know as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene, which localizes to the long arm of chromosome 2 at position 2q13-2q21 between two fragile sites. Interleukin 1 (IL-1) is a protein with several biological activities regulating host defense and immune responses. The human IL-1 family plays an important role in the pathogenesis of many diseases and functions as a key mediator of the host response to various infectious, inflammatory, and immunologic challenges.
Sequence Similarities: Belongs to the IL-1 family.

分子量

100 kDa

UniProt

P01584

途径

NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome