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HDAC2 抗体 (C-Term)

HDAC2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042622
发货至: 中国
  • 抗原 See all HDAC2 抗体
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    抗原表位
    • 30
    • 15
    • 12
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 464-478, C-Term
    适用
    • 121
    • 86
    • 60
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 107
    • 11
    • 3
    • 1
    克隆类型
    • 100
    • 22
    多克隆
    标记
    • 64
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC2 antibody is un-conjugated
    应用范围
    • 69
    • 42
    • 37
    • 34
    • 28
    • 27
    • 23
    • 18
    • 17
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Histone deacetylase 2(HDAC2) detection. Tested with WB in Human,Mouse,Rat.
    序列
    EDKSKDNSGE KTDTK
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Histone deacetylase 2(HDAC2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: histone deacetylase 2
    Protein Name: Histone deacetylase 2(HD2)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human HDAC2(464-478aa EDKSKDNSGEKTDTK), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product HDAC2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Chen, Xie, Zhao, Wang, Bai, Yin, Jiang, Xie, Jia, Huang et al.: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).

    Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, (2013) (PubMed).

  • 抗原
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    别名
    HDAC2 (HDAC2 产品)
    别名
    HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody
    背景
    Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones(H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al.(1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.

    Synonyms: D10Wsu179e antibody|HD 2 antibody|HD2 antibody|HDAC 2 antibody|Hdac2 antibody|HDAC2_HUMAN antibody|Histone deacetylase 2(HD2) antibody|histone deacetylase 2 antibody|OTTHUMP00000017046 antibody|OTTHUMP00000227077 antibody|OTTHUMP00000227078 antibody|RPD3 antibody|transcriptional regulator homolog RPD3 antibody|YAF1 antibody|YY1 associated factor 1 antibody|YY1 transcription factor binding protein antibody|Yy1bp antibody
    UniProt
    Q92769
    途径
    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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