(1 reference)-
- 抗原 See all F2RL1 抗体
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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抗原表位
- AA 349-383, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This F2RL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Proteinase-activated receptor 2(F2RL1) detection. Tested with WB in Human.
- 序列
- HDFRDHAKNA LLCRSVRTVK QMQVSLTSKK HSRKS
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Proteinase-activated receptor 2(F2RL1) detection. Tested with WB in Human.
Gene Name: coagulation factor II (thrombin) receptor-like 1
Protein Name: Proteinase-activated receptor 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PAR2 (349-383aa HDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKS), different from the related mouse sequence by eight amino acids, and from the related rat sequence by seven amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product F2RL1 Primary Antibody
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anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 368-382), (C-Term), (Intracellular) antibody
F2RL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) antibodyF2RL1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 348-397) antibodyF2RL1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 218-399) antibodyF2RL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (N-Term) antibodyF2RL1 适用: 人 ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal SAM11 unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) antibodyF2RL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 347-363) antibodyF2RL1 适用: 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 260-309) antibodyF2RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (Extracellular Domain) antibodyF2RL1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).
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: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).
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- 抗原
- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
- 别名
- F2RL1 (F2RL1 产品)
- 别名
- par2 antibody, GPR11 antibody, PAR2 antibody, Gpcr11 antibody, PAR-2 antibody, Par2 antibody, Par-2 antibody, Proteinase-activated receptor 2 antibody, F2R like trypsin receptor 1 antibody, coagulation factor II (thrombin) receptor-like 1 antibody, par2 antibody, F2RL1 antibody, F2rl1 antibody
- 背景
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Protease activated receptor 2 (PAR2), also known as coagulation factor II (thrombin) receptor-like 1(F2RL1) or G-protein coupled receptor 11 (GPR11), is a protein that in humans is encoded by the F2RL1 gene. F2RL1 is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. Additionally, PAR2 modulates inflammatory responses and acts as a sensor for proteolytic enzymes generated during infection.
Synonyms: Coagulation factor II receptor like 1 antibody|Coagulation factor II receptor-like 1 antibody|Coagulation factor II thrombin receptor like 1 antibody|F2RL1 antibody|G protein coupled receptor 11 antibody|G-protein coupled receptor 11 antibody|GPR11 antibody|PAR 2 antibody|PAR-2 antibody|PAR2_HUMAN antibody|Protease activated receptor 2 antibody| Proteinase activated receptor 2 antibody| Proteinase-activated receptor 2 antibody|Thrombin receptor like 1 antibody|Thrombin receptor-like 1 antibody - 基因ID
- 2150
- UniProt
- P55085
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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