F2RL1 抗体
(Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| F2RL1 抗体 (C-Term, Intracellular) | 大鼠 | 兔 Polyclonal |
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| F2RL1 抗体 | 人 | 兔 Monoclonal |
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| F2RL1 抗体 (C-Term) | 人, 猴 | 兔 Polyclonal |
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| F2RL1 抗体 | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| F2RL1 抗体 (N-Term) | 人 | 小鼠 Monoclonal |
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| F2RL1 抗体 (AA 348-397) | 人 | 兔 Polyclonal |
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| Recombinant F2RL1 抗体 | 人 | 兔 Monoclonal |
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| F2RL1 抗体 (Extracellular Domain) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| Recombinant F2RL1 抗体 | 人 | Human Monoclonal |
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| F2RL1 抗体 (AA 318-397) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (AA 260-309) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (Extracellular, N-Term) (FITC) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (Extracellular, N-Term) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (AA 15-87) | 人 | 兔 Polyclonal |
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| F2RL1 抗体 (AA 10-90) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| F2RL1 抗体 | 人 | 小鼠 Monoclonal |
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| F2RL1 抗体 (PE) | 人 | 小鼠 Monoclonal |
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| Recombinant F2RL1 抗体 (Cleavage Site) | 人 | 小鼠 Monoclonal |
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| Recombinant F2RL1 抗体 (Cleavage Site, N-Term) | 人, 小鼠, 大鼠, Cynomolgus | Human Monoclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- M (Molecule: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IC (Immunochromatography: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 368-382, C-Term, Intracellular
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8664
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- SAM11
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 348-397
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB5850
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Extracellular Domain
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- BLI (Bio-Layer Interferometry: 所列应用)
- Func (Functional Studies: 所列应用)
- SPR (Surface Plasmon Resonance: 所列应用)
- 适用
- 人
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- PAR650097
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 318-397
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- M (Molecule: 有验证图片)
- LCI (Live Cell Imaging: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 40-52, Extracellular, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- M (Molecule: 有验证图片)
- LCI (Live Cell Imaging: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 40-52, Extracellular, N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 15-87
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 10-90
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- PE
- 抗体亚型
- IgG2a
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1B5
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1, lambda
- 抗原表位
- Cleavage Site
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cynomolgus
- 宿主
- Human
- 克隆形成能力
- Monoclonal
- 克隆
- Ab4999
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG4, lambda
- 抗原表位
- Cleavage Site, N-Term
Latest Publications for our F2RL1 抗体
: "Structural insight into allosteric modulation of protease-activated receptor 2. ..." in: Nature, Vol. 545, Issue 7652, pp. 112-115, (2017) (PubMed).
: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).
: "Hydroxysafflor yellow A inhibits TGF-β1-induced activation of human fetal lung fibroblasts in vitro." in: The Journal of pharmacy and pharmacology, Vol. 68, Issue 10, pp. 1320-30, (2016) (PubMed).
: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
: "Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation." in: Experimental dermatology, Vol. 19, Issue 2, pp. 117-22, (2010) (PubMed).
: "Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling." in: Arthritis and rheumatism, Vol. 62, Issue 4, pp. 952-9, (2010) (PubMed).
: "Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts." in: Bone, Vol. 44, Issue 6, pp. 1143-50, (2009) (PubMed).
: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).
: "Hydroxysafflor yellow A inhibits TGF-β1-induced activation of human fetal lung fibroblasts in vitro." in: The Journal of pharmacy and pharmacology, Vol. 68, Issue 10, pp. 1320-30, (2016) (PubMed).
: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
: "Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation." in: Experimental dermatology, Vol. 19, Issue 2, pp. 117-22, (2010) (PubMed).
: "Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling." in: Arthritis and rheumatism, Vol. 62, Issue 4, pp. 952-9, (2010) (PubMed).
: "Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts." in: Bone, Vol. 44, Issue 6, pp. 1143-50, (2009) (PubMed).
Aliases for F2RL1 抗体
Proteinase-activated receptor 2 (par2) 抗体F2R like trypsin receptor 1 (F2RL1) 抗体
coagulation factor II (thrombin) receptor-like 1 (F2rl1) 抗体
F2R like trypsin receptor 1 (F2rl1) 抗体
Gpcr11 抗体
GPR11 抗体
PAR-2 抗体
Par-2 抗体
par2 抗体
PAR2 抗体
Par2 抗体
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