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TNFRSF10A 抗体 (N-Term)

TNFRSF10A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN303303
发货至: 中国
  • 抗原 See all TNFRSF10A 抗体
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    抗原表位
    • 13
    • 7
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    • 2
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    • 1
    • 1
    • 1
    • 1
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    AA 1-20, N-Term
    适用
    • 82
    • 5
    • 3
    • 1
    • 1
    宿主
    • 46
    • 36
    克隆类型
    • 48
    • 34
    多克隆
    标记
    • 43
    • 8
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    • 3
    • 1
    • 1
    • 1
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    This TNFRSF10A antibody is un-conjugated
    应用范围
    • 41
    • 30
    • 23
    • 19
    • 16
    • 11
    • 6
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody is specific to TNFRSF10A (CD261/TRAILR1).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    DEAE-Column Chromatography
    免疫原
    Synthetic Peptide corresponding to amino acid 1 to 20 of Human DR4 mature protein.
    Top Product
    Discover our top product TNFRSF10A Primary Antibody
  • 应用备注
    Western Blot (1/500-1/1000). Immunohistochemistry on Paraffin Sections (5 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
  • 抗原
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    别名
    CD261 / TRAILR1 (TNFRSF10A 产品)
    别名
    APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
    背景
    Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
    基因ID
    8797
    NCBI登录号
    NP_003835
    UniProt
    O00220
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity
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