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PAPPA 抗体 (AA 95-388)

PAPPA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032301
发货至: 中国
  • 抗原 See all PAPPA 抗体
    PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
    抗原表位
    • 15
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-388
    适用
    • 80
    • 23
    宿主
    • 46
    • 39
    • 1
    克隆类型
    • 47
    • 39
    多克隆
    标记
    • 33
    • 13
    • 11
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAPPA antibody is un-conjugated
    应用范围
    • 48
    • 45
    • 27
    • 18
    • 13
    • 13
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Human partial recombinant protein (AA 95-388) was used as the immunogen for this PAPP-A antibody.
    亚型
    IgG
    Top Product
    Discover our top product PAPPA Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the PAPP-A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PAPP-A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
    别名
    PAPP-A (PAPPA 产品)
    别名
    8430414N03Rik antibody, IGFBP-4ase antibody, PAG1 antibody, PAPP-A antibody, ASBABP2 antibody, DIPLA1 antibody, PAPA antibody, PAPPA1 antibody, Pappa antibody, pappalysin 1 antibody, pregnancy-associated plasma protein A antibody, PAPPA antibody, Pappa antibody, Pappa1 antibody
    背景
    Pappalysin-1, also known as DIPLA1, is a protein that in humans is encoded by the PAPPA gene. PAPP-A is found in the ovarian follicles, follicular fluid, luteal cells, and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males. This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. It has been found that circulating PAPP-A is a disulfide-bridged complex with proMBP in which the subunits of the constituents are present in a 1:1 Molar ratio.
    基因ID
    5069
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