PAPPA 抗体 (AA 95-388)
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北京 101111
Quick Overview for PAPPA 抗体 (AA 95-388) (ABIN3043377)
抗原
See all PAPPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 95-388
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原理
- Anti-PAPP A/PAPPA Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human PAPP A shares 88% amino acid (aa) sequence identity with mouse PAPP A.
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产品特性
- Anti-PAPP A/PAPPA Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAPP A recombinant protein (Position: R95-Q388). Human PAPP A shares 88% amino acid (aa) sequence identity with mouse PAPP A.
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亚型
- IgG
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anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 351-523) antibody
PAPPA 适用: 人 IHC 宿主: 小鼠 Monoclonal PAPPA-2715 unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 1321-1460) antibodyPAPPA 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 351-523) antibodyPAPPA 适用: 人 IHC 宿主: 小鼠 Monoclonal 780M unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 999-1272) antibodyPAPPA 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 317-532) antibodyPAPPA 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 95-302) antibodyPAPPA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 1270-1558) antibodyPAPPA 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal H4 unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 85-194) antibodyPAPPA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G3 unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
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别名
- PAPPA
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背景
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Background: Pappalysin-1, also known as DIPLA1, is a protein that in humans is encoded by the PAPPA gene. It is mapped to 9q33.1. PAPPA is found in the ovarian follicles, follicular fluid, luteal cells, and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males. This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. It has been found that circulating PAPPA is a disulfide-bridged complex with proMBP in which the subunits of the constituents are present in a 1:1 Molar ratio.
Gene Full Name: pappalysin 1
Sequence Similarities: Belongs to the peptidase M43B family.
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分子量
- 180-220 kDa
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基因ID
- 5069
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UniProt
- Q13219
抗原
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