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- 抗原 See all PAPPA 抗体
- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
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抗原表位
- AA 95-388
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAPPA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Pappalysin-1(PAPPA) detection. Tested with WB, IHC-P in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Pappalysin-1(PAPPA) detection. Tested with WB, IHC-P in Human.
Gene Name: pregnancy-associated plasma protein A, pappalysin 1
Protein Name: Pappalysin-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PAPP A recombinant protein (Position: R95-Q388). Human PAPP A shares 88% amino acid (aa) sequence identity with mouse PAPP A.
- 亚型
- IgG
- Top Product
- Discover our top product PAPPA Primary Antibody
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anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 351-523) antibody
PAPPA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PAPPA-2715 unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 1321-1460) antibodyPAPPA 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) antibodyPAPPA 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 351-523) antibodyPAPPA 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-780M unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 317-532) antibodyPAPPA 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 999-1272) antibodyPAPPA 适用: 小鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 95-302) antibodyPAPPA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 1270-1558) antibodyPAPPA 适用: 人 WB, IP, IHC, ICC 宿主: 小鼠 Monoclonal H12 unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 85-194) antibodyPAPPA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA) (AA 1270-1558) antibodyPAPPA 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PAPP A is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
- 别名
- PAPPA (PAPPA 产品)
- 别名
- 8430414N03Rik antibody, IGFBP-4ase antibody, PAG1 antibody, PAPP-A antibody, ASBABP2 antibody, DIPLA1 antibody, PAPA antibody, PAPPA1 antibody, Pappa antibody, pappalysin 1 antibody, pregnancy-associated plasma protein A antibody, PAPPA antibody, Pappa antibody, Pappa1 antibody
- 背景
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Pappalysin-1, also known as DIPLA1, is a protein that in humans is encoded by the PAPPA gene. It is mapped to 9q33.1. PAPPA is found in the ovarian follicles, follicular fluid, luteal cells, and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males. This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. It has been found that circulating PAPPA is a disulfide-bridged complex with proMBP in which the subunits of the constituents are present in a 1:1 Molar ratio.
Synonyms: ASBABP2 antibody|Aspecific BCL2 ARE binding protein 2 antibody|Differentially placenta 1 expressed protein antibody|DIPLA1 antibody|IGF dependent IGFBP 4 protease antibody|IGF-dependent IGFBP-4 protease antibody|IGFBP 4ase antibody|IGFBP-4ase antibody|IGFBP4ase antibody|Insulin like growth factor dependent IGF binding protein 4 protease antibody|Insulin-like growth factor-dependent IGF-binding protein 4 protease antibody|PAPA antibody|PAPP A antibody|PAPP-A antibody|PAPP1_HUMAN antibody|PAPPA antibody|PAPPA1 antibody|Pappalysin 1 precursor antibody|Pappalysin-1 antibody|Pregnancy Associated Plasma Protein A antibody|Pregnancy associated plasma protein A pappalysin 1 antibody|Pregnancy-associated plasma protein A antibody - 基因ID
- 5069
- UniProt
- Q13219
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