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TLR10 抗体 (N-Term)

TLR10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029161
发货至: 中国
  • 抗原 See all TLR10 抗体
    TLR10 (Toll-Like Receptor 10 (TLR10))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 4
    • 3
    • 3
    • 1
    宿主
    • 18
    • 8
    克隆类型
    • 18
    • 8
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR10 antibody is un-conjugated
    应用范围
    • 16
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the N-terminus of human Toll-like receptor 10 (DLKTFEFNKELRYLD) was used as the immunogen for this TLR10 antibody.
    亚型
    IgG
    Top Product
    Discover our top product TLR10 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the TLR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the TLR10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    TLR10 (Toll-Like Receptor 10 (TLR10))
    别名
    TLR10 (TLR10 产品)
    别名
    TLR10 antibody, CD290 antibody, toll like receptor 10 antibody, toll-like receptor 10 antibody, TLR10 antibody, Tlr10 antibody
    背景
    Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al.(2005) determined that the gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al.(2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM(TICAM2), or TRIF (TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.
    UniProt
    Q9BXR5
    途径
    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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