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TLR10 产品

(Toll-Like Receptor 10 (TLR10))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

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Featured TLR10 Categories

TLR10 抗体

High quality antibodies with extensive validation data.

TLR10 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TLR10 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TLR10 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN566483
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7442696
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1871633
Quantity 100 μL
Datasheet Datasheet

Recommended TLR10 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960026
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1161913
Quantity 96 tests
Datasheet Datasheet

Recommended TLR10 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN5648667
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN2752949
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3074050
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TLR10 Products

Mulla, Myrtolli, Tadesse, Stanwood, Gariepy, Guller, Norwitz, Abrahams: "Cutting-edge report: TLR10 plays a role in mediating bacterial peptidoglycan-induced trophoblast apoptosis." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 69, Issue 5, pp. 449-53, (2013) (PubMed).

Park, Lee, Oh, Jung, Park, Myung, Kim, Koh, Lim: "Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation." in: Oncogene, Vol. 30, Issue 2, pp. 201-11, (2011) (PubMed).

Yang, Xie, Deng, Qin: "Expression of soluble Toll-like receptors in pleural effusions." in: Chinese medical journal, Vol. 123, Issue 16, pp. 2225-30, (2010) (PubMed).

Vogel, Fitzgerald, Fenton: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).

Lazarus, Raby, Lange, Silverman, Kwiatkowski, Vercelli, Klimecki, Martinez, Weiss: "TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples." in: American journal of respiratory and critical care medicine, Vol. 170, Issue 6, pp. 594-600, (2004) (PubMed).

McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, (2004) (PubMed).

ONeill, Fitzgerald, Bowie: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).

Bourke, Bosisio, Golay, Polentarutti, Mantovani: "The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells." in: Blood, Vol. 102, Issue 3, pp. 956-63, (2003) (PubMed).

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).

Synonyms and alternative names related to TLR10

toll like receptor 10 (TLR10), toll-like receptor 10 (Tlr10), CD290, TLR10

Protein level used designations for TLR10

  • toll-like receptor 10
  • toll-like receptor 10-like
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