MUC1 抗体
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- 抗原 See all MUC1 抗体
- MUC1 (Mucin 1 (MUC1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MUC1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
- This antibody recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of MUC1 (Mucin-1) or EMA (epithelial membrane antigen). The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. MUC1 / Mucin-1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling through phosphorylations and protein-protein interactions. In immunohistochemical assays, the MUC1 / EMA antibody superbly stains routine formalin/paraffin carcinoma tissues. MUC1 antibody is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- 纯化方法
- Protein G affinity chromatography
- 纯度
- Protein G affinity chromatography
- 免疫原
- Human milk fat globule membranes were used as the immunogen for this EMA antibody.
- 克隆位点
- MUC1-845
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MUC1 Primary Antibody
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anti-Mucin 1 (MUC1) (AA 410-525) antibody
MUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 474-630) antibodyMUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC1-520 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人, 小鼠 IHC, WB, ELISA, IF, FACS, Coat, StM 宿主: 小鼠 Monoclonal MUC1-955 unconjugated
anti-Mucin 1 (MUC1) (AA 1182-1255) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Mucin 1 (MUC1) (AA 66-175) antibodyMUC1 适用: 人 IHC, WB, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3B10B4 unconjugated
anti-Mucin 1 (MUC1) (AA 1098-1255) antibodyMUC1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 404-655) antibodyMUC1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1062-1139) antibodyMUC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the EMA antibody to be titered up or down for optimal performance.
1. No pretreatment needed for FFPE staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2) - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the EMA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- MUC1 (Mucin 1 (MUC1))
- 别名
- EMA (MUC1 产品)
- 别名
- CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
- 背景
- This antibody recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of MUC1 (Mucin-1) or EMA (epithelial membrane antigen). The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. MUC1 / Mucin-1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling through phosphorylations and protein-protein interactions. In immunohistochemical assays, the MUC1 / EMA antibody superbly stains routine formalin/paraffin carcinoma tissues. MUC1 antibody is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- 基因ID
- 4582
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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