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MUC1 抗体 (AA 66-175)

MUC1 适用: 人 IHC, WB, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3B10B4 unconjugated
产品编号 ABIN5611324
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    抗原表位
    • 26
    • 19
    • 16
    • 16
    • 12
    • 8
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    • 6
    • 5
    • 5
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    • 1
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    AA 66-175
    适用
    • 271
    • 58
    • 30
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 198
    • 86
    • 2
    • 1
    小鼠
    克隆类型
    • 176
    • 106
    • 5
    单克隆
    标记
    • 146
    • 26
    • 16
    • 11
    • 11
    • 10
    • 5
    • 5
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    • 2
    • 1
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    This MUC1 antibody is un-conjugated
    应用范围
    • 140
    • 136
    • 102
    • 83
    • 75
    • 48
    • 26
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    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD227 (AA: extra 66-175) expressed in E. coli.
    克隆位点
    3B10B4
    亚型
    IgG1
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    CD227 (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景

    Description: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

    Aliases: MUC1, EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC

    分子量
    122.1 kDa
    基因ID
    4582
    HGNC
    4582
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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