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HDAC2 抗体 (C-Term)

HDAC2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022867
发货至: 中国
  • 抗原 See all HDAC2 抗体
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    抗原表位
    • 30
    • 15
    • 12
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 121
    • 86
    • 60
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 107
    • 11
    • 3
    • 1
    克隆类型
    • 100
    • 22
    多克隆
    标记
    • 64
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC2 antibody is un-conjugated
    应用范围
    • 69
    • 42
    • 37
    • 34
    • 28
    • 27
    • 23
    • 18
    • 17
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    序列
    VHEDSGDEDG EDPDKRISIR ASDKRIACDE EFSDSEDEGE GGRRNVADHK KGAKKARIEE DKKETEDKKT DVKEEDKSKD NSGEKTDTKG TKSEQLSNP
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 390 to the C-terminus of human HDAC2 (NP_001518.3).
    亚型
    IgG
    Top Product
    Discover our top product HDAC2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

    Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." in: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

    Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." in: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

  • 抗原
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    别名
    HDAC2 (HDAC2 产品)
    别名
    HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody
    背景
    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.,HD2,RPD3,YAF1,HDAC2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC2
    分子量
    51 kDa/55 kDa
    基因ID
    3066
    UniProt
    Q92769
    途径
    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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