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Androgen Receptor 抗体

AR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022798
发货至: 中国
  • 抗原 See all Androgen Receptor (AR) 抗体
    Androgen Receptor (AR)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 256
    • 50
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    克隆类型
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    多克隆
    标记
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    This Androgen Receptor antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human AR
    亚型
    IgG
    Top Product
    Discover our top product AR Primary Antibody
  • 应用备注
    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C/-80 °C
  • Xue, Zhang, Wang, Zhang, Xiang, Wang, Wang, Li, Zhang, Zou, Wang, Wu, Lu, Chen, Ding, Li, Xu: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." in: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).

  • 抗原
    Androgen Receptor (AR)
    别名
    AR (AR 产品)
    别名
    AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
    背景
    Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding. This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer.
    Synonyms: KD, AIS, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1, HUMARA
    基因ID
    367
    UniProt
    P10275
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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