Androgen Receptor 产品
(Androgen Receptor (AR))
Categories
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured Androgen Receptor Categories
Androgen Receptor 抗体
High quality antibodies with extensive validation data.
Androgen Receptor ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Androgen Receptor 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Androgen Receptor 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (5)
- (1)
Cat. No.
ABIN1871059
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
- (1)
Cat. No.
ABIN2857043
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (5)
Cat. No.
ABIN1724724
Quantity
100 μL
Datasheet
Datasheet
Recommended Androgen Receptor ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964823
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974982
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953700
Quantity
96 tests
Datasheet
Datasheet
Recommended Androgen Receptor 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121827
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121826
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345428
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Androgen Receptor Products
: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." in: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." in: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).
: "Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer." in: Journal of translational medicine, Vol. 16, Issue 1, pp. 356, (2018) (PubMed).
: "Effects of low dose of bisphenol A on the proliferation and mechanism of primary cultured prostate epithelial cells in rodents." in: Oncology letters, Vol. 14, Issue 3, pp. 2635-2642, (2017) (PubMed).
: "Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo." in: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 1, pp. 53-62, (2016) (PubMed).
: "Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 980583, (2016) (PubMed).
: "Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1361-1366, (2016) (PubMed).
: "Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and ..." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 905-908, (2015) (PubMed).
: "Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model." in: Oncology letters, Vol. 10, Issue 3, pp. 1819-1825, (2015) (PubMed).
: "Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients." in: International journal of molecular sciences, Vol. 14, Issue 8, pp. 16656-71, (2013) (PubMed).
Synonyms and alternative names related to Androgen Receptor
androgen receptor (AR), androgen receptor (Ar), androgen receptor (ar), AIS, Andr, AR, AW320017, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, TfmProtein level used designations for Androgen Receptor
- androgen nuclear receptor variant 2
- dihydrotestosterone receptor
- nuclear receptor subfamily 3 group C member 4
- testicular feminization
- androgen receptor (Testicular feminization), same as Tfm
- androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
- androgen receptor AR
- AR-A
- Ar beta
- androgen receptor
- prostate androgen receptor
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