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Androgen Receptor 抗体

AR 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2H8 unconjugated
产品编号 ABIN1724724
发货至: 中国
  • 抗原 See all Androgen Receptor (AR) 抗体
    Androgen Receptor (AR)
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Androgen Receptor antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human AR expressed in E. coli.
    克隆位点
    2H8
    亚型
    IgG1
    Top Product
    Discover our top product AR Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Yu, Han, Shao, Wu, Zhao, Liu, Sun, Tang, Xia: "Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo." in: Chinese medical journal, Vol. 122, Issue 22, pp. 2779-83, (2009) (PubMed).

    Hsu, Lan, Tsai, Ou, Cheng, Tsai, Kang, Tung, Wong, Huang: "Expression of androgen receptor in human placentas from normal and preeclamptic pregnancies." in: Taiwanese journal of obstetrics & gynecology, Vol. 48, Issue 3, pp. 262-7, (2009) (PubMed).

    Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: "DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells." in: Cancer research, Vol. 67, Issue 10, pp. 4630-7, (2007) (PubMed).

  • 抗原
    Androgen Receptor (AR)
    别名
    Androgen receptor (AR 产品)
    别名
    AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
    背景

    Description: The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

    Aliases: NR3C4, KD, AIS, SMAX1, HUMARA, AR

    分子量
    110 kDa
    基因ID
    367
    HGNC
    367
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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