电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

POMC 抗体 (AA 1-267)

POMC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3017231
发货至: 中国
  • 抗原 See all POMC 抗体
    POMC (Proopiomelanocortin (POMC))
    抗原表位
    • 16
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-267
    适用
    • 69
    • 42
    • 40
    • 2
    • 2
    • 1
    • 1
    宿主
    • 51
    • 37
    • 2
    • 1
    克隆类型
    • 52
    • 39
    多克隆
    标记
    • 63
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POMC antibody is un-conjugated
    应用范围
    • 34
    • 34
    • 32
    • 30
    • 22
    • 13
    • 13
    • 13
    • 12
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    MPRSCCSRSG ALLLALLLQA SMEVRGWCLE SSQCQDLTTE SNLLECIRAC KPDLSAETPM FPGNGDEQPL TENPRKYVMG HFRWDRFGRR NSSSSGSSGA GQKREDVSAG EDCGPLPEGG PEPRSDGAKP GPREGKRSYS MEHFRWGKPV GKKRRPVKVY PNGAEDESAE AFPLEFKREL TGQRLREGDG PDGPADDGAG AQADLEHSLL VAAEKKDEGP YRMEHFRWGS PPKDKRYGGF MTSEKSQTPL VTLFKNAIIK NAYKKGE
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-267 of human POMC (NP_000930.1).
    亚型
    IgG
    Top Product
    Discover our top product POMC Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    POMC (Proopiomelanocortin (POMC))
    别名
    POMC (POMC 产品)
    别名
    MSH antibody, ACTH antibody, pomc antibody, SI:bZ36D5.1 antibody, SI:bZ36D5.4 antibody, si:bz36d5.2 antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, NPP antibody, POC antibody, Pomc2 antibody, proopiomelanocortin a antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, pomca antibody, Pomc antibody, POMC antibody
    背景
    This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.,POMC,ACTH,CLIP,LPH,MSH,NPP,POC,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,POMC
    分子量
    29 kDa
    基因ID
    5443
    UniProt
    P01189
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
You are here:
客服