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POMC 抗体

(Proopiomelanocortin (POMC))
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
POMC 抗体  (C-Term) POMC 抗体  (C-Term) POMC 抗体 (C-Term) (ABIN185387)

Verified POMC 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC, WB 宿主: 山羊 Polyclonal unconjugated

POMC 抗体  (AA 1-267) POMC 抗体  (AA 1-267) POMC 抗体 (AA 1-267) (ABIN519039)

POMC 适用: 人 IP, WB 宿主: 兔 Polyclonal unconjugated

POMC 抗体  (AA 1-150) POMC 抗体  (AA 1-150) POMC 抗体 (AA 1-150) (ABIN5542293)

POMC 适用: 人 ELISA, FACS, ICC, IHC, WB 宿主: 小鼠 Monoclonal 6D2B5 unconjugated

POMC 抗体 by Grade

Find POMC 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

POMC 抗体 by 适用

Find POMC 抗体 for a variety of species such as anti-Human POMC, anti-Rat POMC, anti-Mouse POMC. The species listed below are among those available. Click on a link to go to the corresponding products.

POMC 抗体 by 应用范围

Find POMC 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

POMC 抗体 by 抗体来源

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POMC 抗体 by 抗原表位

Find POMC 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

POMC 抗体 by 克隆形成能力

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POMC 抗体 by 克隆

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POMC 抗体 by 标记

Find POMC 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular POMC 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application Coat, ELISA, FACS, IF, IHC, StM
Validations
  • (4)
Cat. No. ABIN6940336
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, WB
Validations
  • (1)
  • (3)
Cat. No. ABIN1077682
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (p)
Validations
  • (2)
  • (3)
Cat. No. ABIN3043901
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (3)
Cat. No. ABIN5542292
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7254256
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7242302
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN562315
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application Coat, ELISA, IHC, StM
Validations
  • (2)
Cat. No. ABIN6940339
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, StM
Validations
  • (2)
Cat. No. ABIN6940344
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1078461
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1860275
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (3)
  • (1)
Cat. No. ABIN673209
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN6266262
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC
Validations
  • (1)
  • (1)
Cat. No. ABIN542611
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN519036
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our POMC 抗体

Muhsin, Bentley, Bai, Goldsworthy, Cox: "A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 31, Issue 1-2, pp. 17-29, (2020) (PubMed).

Mandal, Briski: "Hindbrain dorsal vagal complex AMPK controls hypothalamic gluco-regulatory transmitter and counter-regulatory hormone responses to hypoglycemia." in: Brain research bulletin, Vol. 144, pp. 171-179, (2019) (PubMed).

Wang, Khor, Cai: "Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice." in: The Journal of biological chemistry, Vol. 294, Issue 13, pp. 4946-4955, (2019) (PubMed).

Shakya, Shrestha, Briski: "Hindbrain 5'-Adenosine Monophosphate-activated Protein Kinase Mediates Short-term Food Deprivation Inhibition of the Gonadotropin-releasing Hormone-Luteinizing Hormone Axis: Role of Nitric Oxide." in: Neuroscience, Vol. 383, pp. 46-59, (2019) (PubMed).

Kim, Shi, Somlo, Haataja, Song, Long, Nillni, Low, Arvan, Myers, Qi: "Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity." in: The Journal of clinical investigation, Vol. 128, Issue 3, pp. 1125-1140, (2018) (PubMed).

Klasvogt, Zuschratter, Schmidt, Kröber, Vorwerk, Wolter, Isermann, Wimmers, Rothkötter, Nossol: "Air-liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2." in: Cell death discovery, Vol. 3, pp. 17001, (2017) (PubMed).

Trebak, Dubuc, Arabo, Alaoui, Boukhzar, Maucotel, Picot, Cherifi, Duparc, Leprince, Prévost, Anouar, Magoul, Chartrel: "A potential role for the secretogranin II-derived peptide EM66 in the hypothalamic regulation of feeding behaviour." in: Journal of neuroendocrinology, Vol. 29, Issue 3, (2017) (PubMed).

Xie, Wang, Li, Chao, Yue: "Early Repeated Administration of CXCR4 Antagonist AMD3100 Dose-Dependently Improves Neuropathic Pain in Rats After L5 Spinal Nerve Ligation." in: Neurochemical research, Vol. 41, Issue 9, pp. 2289-99, (2016) (PubMed).

Huo, Liu, Wang, Zhang, Wang, Yang, Sun, Xu: "Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury." in: Neural regeneration research, Vol. 7, Issue 22, pp. 1729-35, (2015) (PubMed).

Nakamoto, Nishinaka, Sato, Mankura, Koyama, Kasuya, Tokuyama: "Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain." in: PLoS ONE, Vol. 8, Issue 12, pp. e81563, (2013) (PubMed).

Aliases for POMC 抗体

proopiomelanocortin a (pomca) 抗体
pro-opiomelanocortin-alpha (Pomc) 抗体
proopiomelanocortin (POMC) 抗体
proopiomelanocortin (Pomc) 抗体
ACTH 抗体
alpha-MSH 抗体
alphaMSH 抗体
BE 抗体
Beta-LPH 抗体
beta-MSH 抗体
Clip 抗体
CLIP 抗体
Gamma-LPH 抗体
gamma-MSH 抗体
LPH 抗体
MSH 抗体
Npp 抗体
NPP 抗体
POC 抗体
pomc 抗体
Pomc-1 抗体
Pomc1 抗体
Pomc2 抗体
SI:bZ36D5.1 抗体
si:bz36d5.2 抗体
SI:bZ36D5.4 抗体
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