IL-1 beta 抗体
Quick Overview for IL-1 beta 抗体 (ABIN299326)
抗原
See all IL-1 beta (IL1B) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
 - Recognizes human IL-1 beta. Neutralizes the biological activity of recombinant humanIL-1b and natural human IL-1b. Will not neutralize the biological activity of recombinant mouse IL-1b, recombinant human IL-1a, or recombinant mouse IL-1a. Based on direct ELISA results, this antibody shows less than 10 % cross-reactivity with recombinant mouse IL-1b, recombinant porcine IL-1b, recombinant rat IL-1b and recombinant crIL-1b.
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纯化方法
 - Immunoaffinity purified
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免疫原
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                        Recombinant human IL-1 beta.
Type of Immunogen: Recombinant protein - 
                                            
亚型
 - IgG
 
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应用备注
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                        Approved: ELISA (0.5 - 1 μg/mL), Neut, WB (0.1 - 0.2 μg/mL)
Usage: Suitable for use in ELISA, Western Blot, and Neutralization of bioactivity. Direct ELISA: 0.5-1 μg/mL. Detection limit for rhIL-1bis ~1.5 ng/well. Western Blot: 0.1-0.2 μg/mL. Detection limit for rhIL-1b is ~0.5 ng/lane under both non-reducing and reducing conditions. - 
                                            
说明
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Target Species of Antibody: Human
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Sterile PBS
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浓度
 - Lot specific
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缓冲液
 - Lyophilized from PBS, 5 % trehalose
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注意事项
 - Avoid freeze-thaw cycles.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
 
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
 - IL1B
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背景
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                        Name/Gene ID: IL1B
Family: IL-1
Synonyms: IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta - 
                                            
基因ID
 - 3553
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UniProt
 - P01584
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途径
 - NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
 
抗原
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