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IL-1 beta 抗体 (Biotin)

IL1B 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
产品编号 ABIN288401
发货至: 中国
  • 抗原 See all IL-1 beta (IL1B) 抗体
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    适用
    • 120
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    宿主
    • 173
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    山羊
    克隆类型
    • 178
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    • 1
    多克隆
    标记
    • 131
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    This IL-1 beta antibody is conjugated to Biotin
    应用范围
    • 179
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    过滤
    Filtered
    免疫原
    IL1 b antibody (biotin) was raised in goat using E. Coli derived recombinant human IL1?/IL1 2 as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product IL1B Primary Antibody
  • 应用备注
    ELISA: 2-8 µg/mL, IHC: 515 µg/mL, WB: 0.1 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute to a concentration of 50 µg/mL with 1 mL of sterile 20 mM Trizma Base, 150 mM NaCl, pH 7.3 containing 0.1 % BSA.
    浓度
    Lot specific
    缓冲液
    Lyophilized from sterile filtered PBS solution with BSA.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    别名
    IL1b (IL1B 产品)
    别名
    IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
    背景
    IL1 is a name that designates two pleiotropic cytokines, IL1 alpha (IL1F1) and IL1Beta (IL1F2), which are the products of distinct genes. IL1 alpha and IL1Beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1 alpha and IL1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL1 RI binds directly to IL1 alpha or IL1Beta and then associates with IL1 R accessory protein (IL1 R3/IL1 R AcP) to form a highaffinity receptor complex that is competent for signal transduction. IL1 RII has high affinity for IL1Beta but functions as a decoy receptor and negative regulator of IL1Beta activity.
    途径
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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