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- 抗原 See all PTPN1 抗体
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to PTP1B (protein tyrosine phosphatase, non-receptor type 1)
PTP1B antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human PTP1B. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PTPN1 Primary Antibody
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibody
PTPN1 适用: 人, 猴, 犬 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 40-246) antibodyPTPN1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4F8F11 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-100) antibodyPTPN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibodyKO Validated PTPN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (pSer50) antibodyPTPN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibodyPTPN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 1G3 unconjugated Recombinant Antibody
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (N-Term) antibodyPTPN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 40-246) antibodyPTPN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F8F2 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 23-53), (N-Term) antibodyPTPN1 适用: 人 WB 宿主: 兔 Polyclonal RB7011 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 221-249) antibodyPTPN1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41801 unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
- 别名
- protein tyrosine phosphatase non-receptor type 1 (PTPN1 产品)
- 别名
- PTPN1 antibody, PTP1B antibody, PTP-1B antibody, PTP-HA2 antibody, Ptp antibody, ptp1b antibody, wu:fk54h03 antibody, CPTP1 antibody, protein tyrosine phosphatase, non-receptor type 1 antibody, protein tyrosine phosphatase, non-receptor type 1 L homeolog antibody, PTPN1 antibody, Ptpn1 antibody, ptpn1 antibody, ptpn1.L antibody
- 背景
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The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
Cellular Localization: Endoplasmic reticulum membrane, Peripheral membrane protein, Cytoplasmic side - 分子量
- 50 kDa
- 基因ID
- 5770
- UniProt
- P18031
- 途径
- TLR signaling, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling
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