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ACVR2B 抗体 (Center)

ACVR2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856085
发货至: 中国
  • 抗原 See all ACVR2B 抗体
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    抗原表位
    • 15
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    Center
    适用
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    宿主
    • 70
    • 7
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    克隆类型
    • 75
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    多克隆
    标记
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    This ACVR2B antibody is un-conjugated
    应用范围
    • 75
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    Western Blotting (WB)
    交叉反应
    大鼠, 猪
    交叉反应 (详细)
    Rat (100 %), Pig (100 %)
    产品特性
    Rabbit Polyclonal antibody to Activin Receptor Type IIB (activin A receptor, type IIB)
    Activin Receptor Type IIB antibody [N1C1]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Activin Receptor Type IIB. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ACVR2B Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    说明

    Positive Control: U87-MG

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    别名
    Activin Receptor Type IIB (ACVR2B 产品)
    别名
    ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

    分子量
    58 kDa
    基因ID
    93
    途径
    Hormone Transport, Cancer Immune Checkpoints
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