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FRS2 抗体 (Center)

FRS2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855603
发货至: 中国
  • 抗原 See all FRS2 抗体
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    抗原表位
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 63
    • 25
    • 19
    • 2
    人, 小鼠
    宿主
    • 73
    • 6
    • 2
    • 1
    克隆类型
    • 78
    • 4
    多克隆
    标记
    • 39
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FRS2 antibody is un-conjugated
    应用范围
    • 59
    • 42
    • 14
    • 14
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Rabbit Polyclonal antibody to FRS2 (fibroblast growth factor receptor substrate 2)
    FRS2 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human FRS2. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: H1299 , HeLaS3

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Bitzer, Spahn, Babaei, Horger, Singer, Schulze-Osthoff, Missios, Gatidis, Nann, Mattern, Scheble, Nikolaou, Armeanu-Ebinger, Schulze, Schroeder, Biskup, Beha, Claassen, Ruhm, Poso, Malek: "Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma." in: NPJ precision oncology, Vol. 5, Issue 1, pp. 80, (2021) (PubMed).

  • 抗原
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    别名
    FRS2 (FRS2 产品)
    别名
    frs2 antibody, wu:fd21h10 antibody, zgc:91973 antibody, FRS2A antibody, FRS2alpha antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, 4732458E18 antibody, C330018A15Rik antibody, Frs2alpha antibody, fibroblast growth factor receptor substrate 2 antibody, fibroblast growth factor receptor substrate 2b antibody, FRS2 antibody, frs2b antibody, Frs2 antibody
    背景
    Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

    Cellular Localization: Endomembrane system
    分子量
    57 kDa
    基因ID
    10818
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
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