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FRS2 抗体 (Tyr196)

The 兔 多克隆 anti-FRS2 antibody (ABIN7180012) specifically detects FRS2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7180012
发货至: 中国
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Quick Overview for FRS2 抗体 (Tyr196) (ABIN7180012)

抗原

See all FRS2 抗体
FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

适用

  • 64
  • 22
  • 21
  • 2

宿主

  • 77
  • 6
  • 1
  • 1

克隆类型

  • 70
  • 15
多克隆

标记

  • 45
  • 5
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 1
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This FRS2 antibody is un-conjugated

应用范围

  • 68
  • 37
  • 18
  • 17
  • 14
  • 14
  • 13
  • 7
  • 5
  • 4
  • 4
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 15
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
    Tyr196

    原理

    FRS2 (Ab-196) Antibody

    交叉反应

    小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

    别名

    FRS2

    背景

    Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Xu H., J. Biol. Chem. 273:17987-17990(1998).
    Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).

    Aliases: FGFR signaling adaptor SNT antibody, FGFR signalling adaptor antibody, FGFR substrate 2 antibody, FGFR-signaling adaptor SNT antibody, Fibroblast growth factor receptor substrate 2 antibody, FRS 2 antibody, FRS2 antibody, FRS2_HUMAN antibody, FRS2A antibody, FRS2alpha antibody, SNT 1 antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, Suc 1 Associated Neurotrophic Factor Target antibody, Suc1 associated neurotrophic factor target 1 antibody, Suc1-associated neurotrophic factor target 1 antibody

    UniProt

    Q8WU20

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
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