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HSP27 抗体 (pSer82) (Alexa Fluor 594)

HSPB1 适用: 人, 大鼠, 小鼠 WB, FACS 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2814547
发货至: 中国
  • 抗原 See all HSP27 (HSPB1) 抗体
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    抗原表位
    • 41
    • 37
    • 27
    • 16
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    pSer82
    适用
    • 298
    • 103
    • 89
    • 24
    • 14
    • 14
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    • 11
    • 6
    • 6
    • 4
    • 3
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 236
    • 66
    克隆类型
    • 205
    • 96
    多克隆
    标记
    • 138
    • 23
    • 17
    • 13
    • 12
    • 8
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    This HSP27 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 255
    • 103
    • 102
    • 95
    • 69
    • 49
    • 49
    • 46
    • 41
    • 40
    • 16
    • 12
    • 10
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human HSP27 around the phosphorylation site of Ser82
    亚型
    IgG
    Top Product
    Discover our top product HSPB1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    别名
    HSP27 (HSPB1 产品)
    别名
    CMT2F antibody, HMN2B antibody, HS.76067 antibody, HSP27 antibody, HSP28 antibody, Hsp25 antibody, SRP27 antibody, 27kDa antibody, Hsp27 antibody, cb153 antibody, cb660 antibody, hsp1 antibody, hsp25 antibody, hsp27 antibody, id:ibd2821 antibody, sb:cb660 antibody, zgc:103437 antibody, HSPB1 antibody, cmt2f antibody, hs.76067 antibody, hsp28 antibody, heat shock protein family B (small) member 1 antibody, heat shock protein 1 antibody, heat shock protein, alpha-crystallin-related, 1 antibody, heat shock protein family B (small) member 1 L homeolog antibody, HSPB1 antibody, Hspb1 antibody, hspb1 antibody, hspb1.L antibody
    背景

    Synonyms: HSP27Ser82,Heat shock 27 kDa protein, 28 kDa heat shock protein, CMT2F, DKFZp586P1322, Estrogen regulated 24 kDa protein, Estrogen-regulated 24 kDa protein, Heat shock 25 kDa protein 1, Heat shock 25 kDa protein 1, Heat shock 27 kDa protein, Heat shock 27kD protein 1, Heat shock 27 kDa protein 1, Heat shock 27 kDa protein 1, Heat shock 28 kDa protein 1, Heat shock 28 kDa protein 1, Heat Shock Protein 27, Heat Shock Protein 27, Heat shock protein beta 1, Heat shock protein beta-1, Heat Shock Protein27, Heat Shock Protein27, HMN2B, HS.76067, Hsp 25, Hsp 25, Hsp 27, Hsp 27, Hsp 28, Hsp 28, Hsp B1, Hsp B1, Hsp25, Hsp25, HSP27, Hsp28, Hsp28, HspB1, HspB1, HSPB1_HUMAN, SRP27, Stress responsive protein 27, Stress-responsive protein 27.

    Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq].Hsp27, also referred to as the Estrogen regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50 % homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen responsive nature of Hsp27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.

    基因ID
    3315
    途径
    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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