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FIP200 抗体 (AA 501-600) (Alexa Fluor 594)

RB1CC1 适用: 小鸡 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2805841
发货至: 中国
  • 抗原 See all FIP200 (RB1CC1) 抗体
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    抗原表位
    • 14
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    适用
    • 28
    • 21
    • 15
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    小鸡
    宿主
    • 53
    • 2
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 20
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    This FIP200 antibody is conjugated to Alexa Fluor 594
    应用范围
    • 35
    • 29
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鸡
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RB1CC1
    亚型
    IgG
    Top Product
    Discover our top product RB1CC1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    别名
    RB1CC1 (RB1CC1 产品)
    别名
    DKFZp459E2330 antibody, CC1 antibody, FIP200 antibody, 2900055E04Rik antibody, 5930404L04Rik antibody, Cc1 antibody, LaXp180 antibody, RB1 inducible coiled-coil 1 antibody, RB1 inducible coiled-coil 1 L homeolog antibody, RB1-inducible coiled-coil 1 antibody, RB1CC1 antibody, rb1cc1.L antibody, rb1cc1 antibody, Rb1cc1 antibody
    背景

    Synonyms: CC1, ATG17, FIP200, PPP1R131, RB1-inducible coiled-coil protein 1, FAK family kinase-interacting protein of 200 kDa, RB1CC1, KIAA0203, RBICC

    Background: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

    基因ID
    9821
    UniProt
    Q8TDY2
    途径
    Regulation of Cell Size, Autophagy
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