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DR3/LARD 抗体 (Middle Region)

TNFRSF25 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792146
发货至: 中国
  • 抗原 See all DR3/LARD (TNFRSF25) 抗体
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    抗原表位
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    Middle Region
    适用
    • 81
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    • 2
    • 1
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    人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬
    宿主
    • 73
    • 10
    克隆类型
    • 72
    • 10
    多克隆
    标记
    • 39
    • 6
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    • 2
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    This DR3/LARD antibody is un-conjugated
    应用范围
    • 72
    • 35
    • 26
    • 26
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
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    Western Blotting (WB)
    序列
    GRFRDQQYEM LKRWRQQQPA GLGAVYAALE RMGLDGCVED LRSRLQRGP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against TNFRSF25. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TNFRSF25
    Top Product
    Discover our top product TNFRSF25 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 372 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
    别名
    TNFRSF25 (TNFRSF25 产品)
    别名
    APO-3 antibody, DDR3 antibody, DR3 antibody, LARD antibody, TNFRSF12 antibody, TR3 antibody, TRAMP antibody, WSL-1 antibody, WSL-LR antibody, Tnfrsf12 antibody, Wsl antibody, TNFRSF25 antibody, TNF receptor superfamily member 25 antibody, tumor necrosis factor receptor superfamily, member 25 antibody, TNFRSF25 antibody, Tnfrsf25 antibody
    背景
    TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
    Alias Symbols: APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
    Protein Interaction Partner: RIPK1, TRADD, UBC, TRAF2, MAPK1, TNFSF15, BAG4, TNFSF12, TNFRSF1A, TNFRSF25, NOL3, DAP3,
    Protein Size: 372
    分子量
    38 kDa
    基因ID
    8718
    NCBI登录号
    NM_148967, NP_683868
    UniProt
    Q93038
    途径
    Apoptosis
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