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- 抗原 See all DR3/LARD (TNFRSF25) 抗体
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DR3/LARD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
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Rabbit Polyclonal antibody to DR3 (tumor necrosis factor receptor superfamily, member 25)
DR3 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human DR3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF25 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) antibody
TNFRSF25 适用: 人 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 4G12H11 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (AA 351-417) antibodyTNFRSF25 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (AA 240-426) antibodyTNFRSF25 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (AA 28-124) antibodyTNFRSF25 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E3 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) antibody (PE)TNFRSF25 适用: 人 FACS 宿主: 小鼠 Monoclonal JD3 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (AA 221-417) antibodyTNFRSF25 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (Extracellular Domain) antibodyTNFRSF25 适用: 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (C-Term) antibodyTNFRSF25 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (AA 24-199) antibodyTNFRSF25 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A16 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) (C-Term) antibodyTNFRSF25 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: Raji , K562
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- 别名
- DR3 (TNFRSF25 产品)
- 别名
- APO-3 antibody, DDR3 antibody, DR3 antibody, LARD antibody, TNFRSF12 antibody, TR3 antibody, TRAMP antibody, WSL-1 antibody, WSL-LR antibody, Tnfrsf12 antibody, Wsl antibody, TNFRSF25 antibody, TNF receptor superfamily member 25 antibody, tumor necrosis factor receptor superfamily, member 25 antibody, TNFRSF25 antibody, Tnfrsf25 antibody
- 背景
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Cellular Localization: Isoform 1: Cell membrane, Single-pass type I membrane protein , Isoform 2: Cell membrane, Single-pass type I membrane protein , Isoform 9: Cell membrane, Single-pass type I membrane protein , Isoform 11: Cell membrane, Single-pass type I membrane protein - 分子量
- 45 kDa
- 基因ID
- 8718
- 途径
- Apoptosis
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