TNFRSF1B 抗体 (N-Term)
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- 抗原 See all TNFRSF1B 抗体
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF1B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SDQVETQACT REQNRICTCR PGWYCALSKQ EGCRLCAPLR KCRPGFGVAR
- 预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against TNFRSF1B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product TNFRSF1B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 461 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Barrier Perturbation in Porcine Peyer's Patches by Tumor Necrosis Factor is Associated With a Dysregulation of Claudins." in: Frontiers in physiology, Vol. 13, pp. 889552, (2022) (PubMed).
: "Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1." in: International journal of molecular sciences, Vol. 22, Issue 16, (2021) (PubMed).
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Barrier Perturbation in Porcine Peyer's Patches by Tumor Necrosis Factor is Associated With a Dysregulation of Claudins." in: Frontiers in physiology, Vol. 13, pp. 889552, (2022) (PubMed).
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- 抗原
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- 别名
- TNFRSF1B (TNFRSF1B 产品)
- 别名
- CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody
- 背景
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Alias Symbols: CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Protein Interaction Partner: LTA, TNF, ADAM17, CSNK1A1, ZNF420, UBQLN1, TRAF1, PKN1, CD14, RIPK1, TRADD, TRAF2, TNFRSF1A, CHUK, TRAF6, TRAF3, ASB3, UBC, HIVEP3, TRAIP, TDP2, CAV1, STAT1, BMX, FANCD2, KRT18, SMURF2, TRIM37, TNFRSF1B,
Protein Size: 461 - 分子量
- 46 kDa
- 基因ID
- 7133
- NCBI登录号
- NM_001066, NP_001057
- UniProt
- P20333
- 途径
- NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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