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- 抗原 See all HLA-DPB1 抗体
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
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抗原表位
- Middle Region
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适用
- 人, 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DPB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KRAVPDRMCR HNYELGGPMT LQRRVQPRVN VSPSKKGPLQ HHNLLVCHVT
- 预测反应
- Dog: 86%, Human: 100%, Rabbit: 93%
- 产品特性
- This is a rabbit polyclonal antibody against HLA-DPB1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product HLA-DPB1 Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibody
HLA-DPB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) (AA 1-258) antibodyHLA-DPB1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 6C6 unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) (AA 77-105) antibodyHLA-DPB1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB33626 unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) (AA 101-210) antibodyHLA-DPB1 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibodyHLA-DPB1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibodyHLA-DPB1 适用: 人 ELISA, FACS, IF, Coat 宿主: 兔 Monoclonal HLA-DPB1-2862R unconjugated Recombinant Antibody
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) (AA 30-225) antibodyHLA-DPB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibodyHLA-DPB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibodyHLA-DPB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) antibodyHLA-DPB1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 258 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- 别名
- HLA-DPB1 (HLA-DPB1 产品)
- 别名
- PATR-DPB1 antibody, B-LB antibody, B-LB2 antibody, B-LB21 antibody, BLB1 antibody, GSP-BLB1 antibody, DPB1 antibody, HLA-DP antibody, HLA-DP1B antibody, HLA-DPB antibody, major histocompatibility complex, class II, DP beta 1 antibody, Major histocompatibility complex class II beta chain BLB1 antibody, PATR-DPB1 antibody, BLB1 antibody, HLA-DPB1 antibody
- 背景
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HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Alias Symbols: DPB1, HLA-DP1B
Protein Interaction Partner: LZTS2, TRIP6, LGR4, COPB1, RTN4, ROBO2, HLA-DPA1, CD74,
Protein Size: 258 - 分子量
- 26 kDa
- 基因ID
- 3115
- NCBI登录号
- NM_002121, NP_002112
- UniProt
- P04440
- 途径
- TCR Signaling, Cancer Immune Checkpoints
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