ERK2 抗体 (C-Term)
Quick Overview for ERK2 抗体 (C-Term) (ABIN2787870)
抗原
See all ERK2 (MAPK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAPK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1
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anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibody
MAPK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 25-360) antibodyMAPK1 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 261-360) antibodyMAPK1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9H1 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 6F8 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) antibodyMAPK1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 9E9 unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 200-300) antibodyMAPK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (N-Term) antibodyMAPK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 310-360) antibodyMAPK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 360 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
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别名
- MAPK1
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背景
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Protein Interaction Partner: Eif4ebp1, ATF2, RPS6KA3, RAF1, PTGDR, MAP2K6, MAP2K1, MAPK3, HDAC6, TP53, NEDD8, DGCR8, HMGB1, NAV1, PDCD6IP, CEP350, MAPK12, RPS6KA2, MAPK1, PDE4D, MBP, KRAS, SQSTM1, CUEDC2, GAB2, BRAF, RPS6KA1, MAP2K4, MAP2K2, ELK1, NOXA1, TIAL1, GADD45A, MAP3K10, SMAD
Protein Size: 360 -
分子量
- 41 kDa
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基因ID
- 5594
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NCBI登录号
- NM_138957, NP_620407
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UniProt
- P28482
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
抗原
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