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- 抗原 See all LRP1 抗体
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ATYLSGAQVS TITPTSTRQT TAMDFSYANE TVCWVHVGDS AAQTQLKCAR
- 产品特性
- This is a rabbit polyclonal antibody against LRP1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LRP1
- Top Product
- Discover our top product LRP1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 439 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype." in: Journal of lipid research, Vol. 54, Issue 10, pp. 2658-64, (2013) (PubMed).
: "Lead exposure increases levels of ?-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice." in: Neuroscience letters, Vol. 490, Issue 1, pp. 16-20, (2011) (PubMed).
: "Increased beta-amyloid levels in the choroid plexus following lead exposure and the involvement of low-density lipoprotein receptor protein-1." in: Toxicology and applied pharmacology, Vol. 240, Issue 2, pp. 245-54, (2009) (PubMed).
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Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype." in: Journal of lipid research, Vol. 54, Issue 10, pp. 2658-64, (2013) (PubMed).
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- 抗原
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- 别名
- LRP1 (LRP1 产品)
- 别名
- A2MR antibody, APOER antibody, APR antibody, CD91 antibody, IGFBP3R antibody, LRP antibody, LRP1A antibody, TGFBR5 antibody, A2mr antibody, AI316852 antibody, Lrp antibody, LRP-1 antibody, LDL receptor related protein 1 antibody, prolow-density lipoprotein receptor-related protein 1 antibody, low density lipoprotein receptor-related protein 1 antibody, LRP1 antibody, Lrp1 antibody, LOC100414789 antibody
- 背景
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Low-density lipoprotein receptor-related protein 1 (.-2-macroglobulin receptor, LRP1) is a multifunctional endocytic receptor with an important role in regulating the activity of proteinases in the extracellular matrix. It is also involved in intracellular signaling and the subcellular translocation of preassembled signaling complexes from the plasma membrane.
Alias Symbols: APR, LRP, A2MR, CD91, APOER, TGFBR5, IGFBP3R
Protein Interaction Partner: UBC, COPS5, APP, RANBP9, SKIL, CHFR, CUBN, FBXO6, ANKS1B, RIC8B, PID1, CC2D1A, MAPRE1, HNRNPDL, MAPK8IP1, SNRNP70, APOE, CACNA1A, USP3, CAV1, MMP14, SHC1, MMP13, SERPINA1, F9, F8, LPL, HSP90B1, SRC, PDGFB, THBS1, SCN3A, PLAUR, PLAT, SERPINE1, MDK, LIPC, L
Protein Size: 439 - 分子量
- 48 kDa
- 基因ID
- 4035
- NCBI登录号
- NM_002332
- UniProt
- Q07954
- 途径
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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