RFC1 抗体 (Middle Region)
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- 抗原 See all RFC1 抗体
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 豚鼠, 兔, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AQAIYASVLP GELMRGYMTQ FPTFPSWLGK HSSTGKHDRI VQDLALHMSL
- 预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against RFC1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RFC1
- Top Product
- Discover our top product RFC1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1147 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- 别名
- RFC1 (RFC1 产品)
- 别名
- A1 antibody, MHCBFB antibody, PO-GA antibody, RECC1 antibody, RFC antibody, RFC140 antibody, AtRFC1 antibody, replication factor C 1 antibody, replication factor C1 antibody, 140kDa antibody, Alp145 antibody, Recc1 antibody, Replication factor C1 antibody, si:dkey-170e5.1 antibody, zgc:162875 antibody, replication factor C subunit 1 antibody, replication factor C1 antibody, replication factor C (activator 1) 1 antibody, DNA replication factor C complex subunit Rfc1 antibody, RFC1 antibody, Rfc1 antibody, rfc1 antibody
- 背景
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The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.
Alias Symbols: A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Protein Interaction Partner: SPRTN, UBC, PCNA, RPA3, RPA2, RPA1, YWHAQ, SMC1A, RFC4, NOTCH1, WDR18, RBM14, RFC5, RFC3, RFC2, LAMP2, MYOC, SIRT7, SUMO2, HDGF, RAD17, CSNK2B, tat, SAP25, ZSCAN1, SSBP3, PMS1, CEBPA, BRCA1, RFC1, BRD4, HDAC1, CASP3, TCEAL1, CCND1, RELA, CDK4, CHTF18, SMA
Protein Size: 1147 - 分子量
- 128 kDa
- 基因ID
- 5981
- NCBI登录号
- NM_002913, NP_002904
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport
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