RFC1 抗体 (AA 401-500)
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- 抗原 See all RFC1 抗体
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
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抗原表位
- AA 401-500
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RFC1
- 亚型
- IgG
- Top Product
- Discover our top product RFC1 Primary Antibody
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anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (C-Term) antibody
RFC1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 400-700) antibodyRFC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 1-110) antibodyRFC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (Internal Region) antibodyRFC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (C-Term) antibodyRFC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 1-110) antibodyRFC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (Internal Region) antibodyRFC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 1-110) antibodyRFC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 935-984) antibodyRFC1 适用: 人, 小鼠, 豚鼠, 兔, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Replication Factor C (Activator 1) 1, 145kDa (RFC1) (AA 46-64), (N-Term) antibodyRFC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- 别名
- RFC1 (RFC1 产品)
- 别名
- A1 antibody, MHCBFB antibody, PO-GA antibody, RECC1 antibody, RFC antibody, RFC140 antibody, AtRFC1 antibody, replication factor C 1 antibody, replication factor C1 antibody, 140kDa antibody, Alp145 antibody, Recc1 antibody, Replication factor C1 antibody, si:dkey-170e5.1 antibody, zgc:162875 antibody, replication factor C subunit 1 antibody, replication factor C1 antibody, replication factor C (activator 1) 1 antibody, DNA replication factor C complex subunit Rfc1 antibody, RFC1 antibody, Rfc1 antibody, rfc1 antibody
- 背景
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Synonyms: DNA binding Protein PO GA, DNA-binding protein PO-GA, MHC binding factor beta, MHCBFB, RECC1, Replication factor C 140 kDa subunit, Replication factor C, Replication factor C large subunit, Replication factor C subunit 1, Replication factor C1, RF-C 140 kDa subunit, RFC1, RFC1_HUMAN, RFC140, RFC140 Replication Factor C 140 kDa subunit, A1 140 kDa subunit, A1 P145 Activator 1 large subunit, Activator 1 140 kDa subunit, Activator 1 large subunit, Activator 1 subunit 1.
Background: Replication factor C (RFC) is an essential DNA polymerase accessory protein that is required for numerous aspects of DNA metabolism, including DNA replication, DNA repair and telomere metabolism. RFC is a heteropentameric complex that recognizes a primer on a template DNA, binds to a primer terminus and loads proliferating cell nuclear antigen (PCNA) onto DNA at primer-template junctions in an ATP-dependent reaction. All five of the RFC subunits share a set of related sequences (RFC boxes) that include nucleotide-binding consensus sequences. Four of the five RFC genes (including RFC1, RFC2, RFC3 and RFC4) have consensus ATP-binding motifs. The small RFC proteins, RFC2, RFC3, RFC4 and RFC5, interact with Rad24, whereas the RFC1 subunit does not. RFC1 is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during FAS-mediated apoptosis. In addition, phosphorylation of the PCNA binding domain of RFC1 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibits DNA synthesis. The human RFC1 gene maps to chromosome 4p14 and encodes the RFC1 subunit.
- 基因ID
- 5981
- UniProt
- P35251
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport
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