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- 抗原 See all SOCS7 抗体
- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LDPKALPPGL ALERTWGPAA GLEAQLAALG LGQPAGPGVK TVGGGCCPCP
- 预测反应
- Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SOCS7. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SOCS7
- Top Product
- Discover our top product SOCS7 Primary Antibody
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anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 6-165) antibody
SOCS7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) antibodySOCS7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (Internal Region) antibodyVerified SOCS7 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 35-84) antibodySOCS7 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 458-486) antibodySOCS7 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 581 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
- 别名
- SOCS7 (SOCS7 产品)
- 别名
- NAP4 antibody, NCKAP4 antibody, SOCS4 antibody, SOCS6 antibody, 2310063P06Rik antibody, C85125 antibody, Nap4 antibody, GB13951 antibody, zgc:175115 antibody, SOCS7 antibody, socs7 antibody, suppressor of cytokine signaling 7 antibody, suppressor of cytokine signaling antibody, SOCS7 antibody, Socs7 antibody, LOC413772 antibody, socs7 antibody
- 背景
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SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: NAP4, NCKAP4
Protein Interaction Partner: SEPT6, SORBS3, STAT5A, STAT3, CUL5, IRS4, PIK3R2, TUBB4B, TUBA1A, IRS2, NCK1, PLCG1, PIK3R1, EGFR, GRB2,
Protein Size: 581 - 分子量
- 64 kDa
- 基因ID
- 30837
- NCBI登录号
- NM_014598, NP_055413
- UniProt
- O14512
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