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SOCS7 抗体 (AA 6-165)

SOCS7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7171009
发货至: 中国
  • 抗原 See all SOCS7 抗体
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 6-165
    适用
    • 40
    • 19
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 1
    克隆类型
    • 40
    多克隆
    标记
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS7 antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    别名
    SOCS7 (SOCS7 产品)
    别名
    NAP4 antibody, NCKAP4 antibody, SOCS4 antibody, SOCS6 antibody, 2310063P06Rik antibody, C85125 antibody, Nap4 antibody, GB13951 antibody, zgc:175115 antibody, SOCS7 antibody, socs7 antibody, suppressor of cytokine signaling 7 antibody, suppressor of cytokine signaling antibody, SOCS7 antibody, Socs7 antibody, LOC413772 antibody, socs7 antibody
    背景

    Background: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

    Aliases: Ash and phospholipase C gamma-binding protein antibody, NAP 4 antibody, NAP 4 Fragment antibody, NAP-4 antibody, NAP4 antibody, Nck antibody, Nck Ash and phospholipase C binding protein antibody, Nck Ash and phospholipase C gamma binding protein antibody, Nck associated protein 4 antibody, Nck-associated protein 4 antibody, NCKAP4 antibody, SH2 domain containing SOCS box protein antibody, SOCS 7 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS6 antibody, Socs7 antibody, SOCS7_HUMAN antibody, Suppressor of cytokine signaling 7 antibody

    UniProt
    O14512
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