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SOCS7 抗体 (AA 458-486)

SOCS7 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029049
发货至: 中国
  • 抗原 See all SOCS7 抗体
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 458-486
    适用
    • 40
    • 19
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 1
    克隆类型
    • 40
    多克隆
    标记
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS7 antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应 (详细)
    Expected species reactivity: Mouse
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 458-486 from the human protein was used as the immunogen for this SOCS7 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SOCS7 Primary Antibody
  • 应用备注
    Titration of the SOCS7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SOCS7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    别名
    SOCS7 (SOCS7 产品)
    别名
    NAP4 antibody, NCKAP4 antibody, SOCS4 antibody, SOCS6 antibody, 2310063P06Rik antibody, C85125 antibody, Nap4 antibody, GB13951 antibody, zgc:175115 antibody, SOCS7 antibody, socs7 antibody, suppressor of cytokine signaling 7 antibody, suppressor of cytokine signaling antibody, SOCS7 antibody, Socs7 antibody, LOC413772 antibody, socs7 antibody
    背景
    Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
    UniProt
    O14512
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