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PAK4 抗体 (Middle Region)

PAK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2498734
发货至: 中国
  • 抗原 See all PAK4 抗体
    PAK4 (P21-Activated Kinase 4 (PAK4))
    抗原表位
    • 14
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 87
    • 55
    • 36
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔
    宿主
    • 81
    • 5
    • 1
    克隆类型
    • 81
    • 6
    多克隆
    标记
    • 43
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK4 antibody is un-conjugated
    应用范围
    • 71
    • 38
    • 20
    • 19
    • 9
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    EPQLAPPACT PAAPAVPGPP GPRSPQREPQ RVSHEQFRAA LQLVVDPGDP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PAK4. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human PAK4
    Top Product
    Discover our top product PAK4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PAK4 (P21-Activated Kinase 4 (PAK4))
    别名
    PAK4 (PAK4 产品)
    别名
    5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
    背景
    PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: -
    Protein Interaction Partner: SH3RF2, HECW2, UBC, LATS2, YWHAQ, YWHAB, SRPK2, SRPK1, FBXO25, YWHAE, APP, POT1, TERF1, YWHAZ, YWHAG, RAN, CDC42, GATAD2A, PAK4, LIMK1, ITGAV, FGFR2, ITGB5, DLST, GRB2, RAC1, LRRK1, SFN, SSH1,
    Protein Size: 591
    分子量
    65 kDa
    基因ID
    10298
    NCBI登录号
    NM_005884, NP_005875
    UniProt
    O96013
    途径
    RTK signaling
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