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IL12RB2 抗体 (Middle Region)

IL12RB2 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782132
发货至: 中国
  • 抗原 See all IL12RB2 抗体
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    抗原表位
    • 15
    • 14
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 兔, 绵羊
    宿主
    • 59
    • 10
    克隆类型
    • 62
    • 7
    多克隆
    标记
    • 28
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL12RB2 antibody is un-conjugated
    应用范围
    • 58
    • 25
    • 19
    • 18
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    DVWYMKRHID YSRQQISLFW KNLSVSEARG KILHYQVTLQ ELTGGKAMTQ
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against IL12RB2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human IL12RB2
    Top Product
    Discover our top product IL12RB2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    别名
    IL12RB2 (IL12RB2 产品)
    别名
    IL12RB2 antibody, A930027I18Rik antibody, IL-12RB2 antibody, Ifnm antibody, interleukin 12 receptor subunit beta 2 antibody, interleukin 12 receptor, beta 2 antibody, IL12RB2 antibody, Il12rb2 antibody
    背景
    The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
    Protein Interaction Partner: SOCS3, IL12RB2, IL12RB1, STAT4, IL12B, JAK2,
    Protein Size: 659
    分子量
    72 kDa
    基因ID
    3595
    途径
    JAK/STAT Signaling
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