IL12RB2 抗体 (C-Term)
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Quick Overview for IL12RB2 抗体 (C-Term) (ABIN952881)
抗原
See all IL12RB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 759-788, C-Term
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特异性
- This antibody detects human IL12RB2 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Purified through a protein A column; followed by peptide affinity purification.
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
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别名
- IL12RB2
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背景
- The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain
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基因ID
- 3595
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NCBI登录号
- NP_001550
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途径
- JAK/STAT Signaling
抗原
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