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IL12RB2 抗体 (C-Term)

The 兔 多克隆 anti-IL12RB2 antibody (ABIN952881) specifically detects IL12RB2 in WB, FACS, IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN952881
发货至: 中国
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Quick Overview for IL12RB2 抗体 (C-Term) (ABIN952881)

抗原

See all IL12RB2 抗体
IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12RB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 759-788, C-Term

    特异性

    This antibody detects human IL12RB2 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Purified through a protein A column; followed by peptide affinity purification.

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

    别名

    IL12RB2

    背景

    The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain

    基因ID

    3595

    NCBI登录号

    NP_001550

    途径

    JAK/STAT Signaling
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