ACVR2B 抗体 (C-Term)
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- 抗原 See all ACVR2B 抗体
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 绵羊, 豚鼠, 斑马鱼, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACVR2B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HDAEARLSAG CVEERVSLIR RSVNGTTSDC LVSLVTSVTN VDLPPKESSI
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against ACVR2B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ACVR2B
- Top Product
- Discover our top product ACVR2B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 303 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 别名
- ACVR2B (ACVR2B 产品)
- 别名
- ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
- 背景
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Alias Symbols: HTX4, ACTRIIB, ActR-IIB
Protein Interaction Partner: GDF2, BMP10, INHBA, PEG10, ERBB2IP, HSP90AA1, SMAD7, SMAD6, SMAD2, IGSF1, SYNJ2BP, SNX6, SNX2, TGFBRAP1, GDF11, MSTN, ACVR1B, SNX1, INHBC, GDF5, INHBB, BMP7, BMP2, ENG, BMP6,
Protein Size: 303 - 分子量
- 33 kDa
- 基因ID
- 93
- NCBI登录号
- NM_001106
- UniProt
- Q13705
- 途径
- Hormone Transport, Cancer Immune Checkpoints
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