ACVRL1 抗体 (N-Term)
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- 抗原 See all ACVRL1 抗体
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Pig, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACVRL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SPHCKGPTCR GAWCTVVLVR EEGRHPQEHR GCGNLHRELC RGRPTEFVNH
- 预测反应
- Dog: 100%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against ACVRL1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVRL1
- Top Product
- Discover our top product ACVRL1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 503 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- 别名
- ACVRL1 (ACVRL1 产品)
- 别名
- ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody
- 背景
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ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: TGFBR1, TGFB1, INHBA, SMAD1, PEG10, NR1H2, FKBP1A, CSNK2B, ENG, BAMBI, HSP90AA1, IGSF1, TSC22D1, SNX6, TGFBRAP1, XIAP, TGFB3, TGFBR2, ACVR2A,
Protein Size: 503 - 分子量
- 55 kDa
- 基因ID
- 94
- NCBI登录号
- NM_000020, NP_000011
- UniProt
- P37023
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