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NKX3-1 抗体 (Middle Region)

NKX3-1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779964
发货至: 中国
  • 抗原 See all NKX3-1 抗体
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    抗原表位
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 70
    • 19
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 56
    • 23
    • 1
    克隆类型
    • 55
    • 25
    多克隆
    标记
    • 46
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NKX3-1 antibody is un-conjugated
    应用范围
    • 56
    • 45
    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    TPTEPESDAH FETYLLDCEH NPGDLASAPQ VTKQPQKRSR AAFSHTQVIE
    预测反应
    Mouse: 100%
    产品特性
    This is a rabbit polyclonal antibody against Nkx3-1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Nkx3-1
    Top Product
    Discover our top product NKX3-1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 237 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    别名
    Nkx3-1 (NKX3-1 产品)
    别名
    Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody
    背景
    Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
    Alias Symbols: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
    Protein Interaction Partner: Fem1b, SP2,
    Protein Size: 237
    分子量
    27 kDa
    基因ID
    18095
    NCBI登录号
    NM_010921, NP_035051
    UniProt
    P97436
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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