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NKX3-1 产品

(NK3 Homeobox 1 (NKX3-1))
This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012].

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Featured NKX3-1 Categories

NKX3-1 抗体

High quality antibodies with extensive validation data.

NKX3-1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

NKX3-1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NKX3-1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN518368
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (4)
  • (4)
Cat. No. ABIN969316
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, Coat, StM
Validations
  • (4)
Cat. No. ABIN6940210
Quantity 100 μg
Datasheet Datasheet

Recommended NKX3-1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958206
Quantity 96 tests
Datasheet Datasheet

Recommended NKX3-1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124181
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312636
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3084442
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NKX3-1 Products

Blee, He, Yang, Ye, Yan, Pan, Ma, Dugdale, Kuehn, Kohli, Jimenez, Chen, Xu, Wang, Huang: "TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 18, pp. 4551-4565, (2018) (PubMed).

Bhatt, Stender, Joshi, Wu, Katzenellenbogen: "OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells." in: Oncogene, Vol. 35, Issue 44, pp. 5722-5734, (2016) (PubMed).

Zhong, Ding, Bohrer, Pan, Liu, Zhang, Sebo, Karnes, Tindall, van Deursen, Huang: "p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis." in: Cancer research, Vol. 74, Issue 6, pp. 1870-80, (2014) (PubMed).

Zhou, Qin, Tien, Gao, Chen, Wang, Hsieh, Xu: "Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17248-56, (2012) (PubMed).

Zhang, Liu, Zhang, Guan, Chen, Cui, Liu, Jiang: "Gene expression profiles in the PC-3 human prostate cancer cells induced by NKX3.1." in: Molecular biology reports, Vol. 37, Issue 3, pp. 1505-12, (2010) (PubMed).

Lee, Jadhav, Ayer, Rojas, Hyong, Lekic, Stier, Martin, Zhang: "The antioxidant effects of melatonin in surgical brain injury in rats." in: Acta neurochirurgica. Supplement, Vol. 102, pp. 367-71, (2009) (PubMed).

Zhang, Fillmore, Zimmer: "Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor." in: Experimental biology and medicine (Maywood, N.J.), Vol. 233, Issue 3, pp. 297-309, (2008) (PubMed).

Jiang, Yu, Zhang, Chen, Liu, Hu, Zhang: "p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line." in: Experimental & molecular medicine, Vol. 38, Issue 6, pp. 625-33, (2007) (PubMed).

Gao, Ouyang, Banach-Petrosky, Borowsky, Lin, Kim, Lee, Shih, Cardiff, Shen, Abate-Shen: "A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 49, pp. 17204-9, (2004) (PubMed).

Kim, Cardiff, Desai, Banach-Petrosky, Parsons, Shen, Abate-Shen: "Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 5, pp. 2884-9, (2002) (PubMed).

Synonyms and alternative names related to NKX3-1

NK3 homeobox 1 L homeolog (nkx3-1.L), NK3 homeobox 1 (NKX3-1), NK3 homeobox 1 (nkx3-1), NK-3 transcription factor, locus 1 (Drosophila) (Nkx3-1), NK3 homeobox 1 (Nkx3-1), bagpipe, BAPX2, Bax, koza, MGC53041, MGC97890, Nkx-3.1, NKX3, nkx3-1, nkx3.1, NKX3.1, nkx3a, NKX3A, si:ch211-67o1.2, Xbagpipe, Xbap

Protein level used designations for NKX3-1

  • NK3 transcription factor related, locus 1
  • NK3 homeobox 1
  • Drosophila NK-3 transcription factor, locus 1
  • homeobox protein NK-3 homolog A
  • homeobox protein Nkx-3.1
  • NK homeobox, family 3, A
  • NK3 transcription factor homolog A
  • NK-3 transcription factor, locus 1
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