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CIITA 抗体 (C-Term)

CIITA 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779823
发货至: 中国
  • 抗原 See all CIITA 抗体
    CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 19
    • 16
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 20
    • 1
    克隆类型
    • 20
    • 1
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CIITA antibody is un-conjugated
    应用范围
    • 14
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MALWESLQQQ GEAQLLQAAE EKFTIEPFKA KSPKDVEDLD RLVQTQRLRN
    预测反应
    Dog: 100%, Human: 79%, Mouse: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against C2TA. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of mouse C2TA
    Top Product
    Discover our top product CIITA Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1078 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
    别名
    C2TA (CIITA 产品)
    别名
    CIITA antibody, C2ta antibody, EG669998 antibody, Gm9475 antibody, C2TA antibody, CIITAIV antibody, MHC2TA antibody, NLRA antibody, Mhc2ta antibody, class II, major histocompatibility complex, transactivator antibody, class II major histocompatibility complex transactivator antibody, MHC class II transactivator antibody, class II transactivator antibody, CIITA antibody, LOC710761 antibody, ciita antibody, LOC100443575 antibody, Ciita antibody, LOC100736732 antibody
    背景
    C2ta is essential for transcriptional activity of the HLA class II promoter, activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
    Alias Symbols: C2ta, Gm9475, EG669998
    Protein Interaction Partner: Rfxank, Ssbp4, Ssbp3, Gmeb1, Cited4, Tcf3, Nfe2, Hoxa2, Ewsr1,
    Protein Size: 1078
    分子量
    119 kDa
    基因ID
    12265
    NCBI登录号
    NM_007575, NP_031601
    UniProt
    Q3U2P0
    途径
    Cancer Immune Checkpoints
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