(3 references)-
- 抗原 See all CIITA 抗体
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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抗原表位
- AA 1
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适用
- Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CIITA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Concentration Definition: by Refractometry
- 免疫原
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The immunogen used for this study was a bacterially produced recombinant FLAG-CIITA corresponding to through 333 of the human protein.
Immunogentype:Recombinant - Top Product
- Discover our top product CIITA Primary Antibody
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anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 945-1130) antibody
CIITA 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (Internal Region) antibodyCIITA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 841-890) antibodyCIITA 适用: 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (C-Term) antibodyCIITA 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 650-750) antibodyCIITA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For immunoblotting a 1:500 dilution is recommended. Researchers should determine optimal titers for other applications.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 90 mg/mL
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "A super enhancer controls expression and chromatin architecture within the MHC class II locus." in: The Journal of experimental medicine, Vol. 217, Issue 2, (2020) (PubMed).
: "Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment." in: Nucleic acids research, Vol. 43, Issue 6, pp. 3128-42, (2015) (PubMed).
: "The 19S proteasome positively regulates histone methylation at cytokine inducible genes." in: Biochimica et biophysica acta, Vol. 1789, Issue 11-12, pp. 691-701, (2009) (PubMed).
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: "A super enhancer controls expression and chromatin architecture within the MHC class II locus." in: The Journal of experimental medicine, Vol. 217, Issue 2, (2020) (PubMed).
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- 抗原
- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
- 别名
- CIITA (CIITA 产品)
- 别名
- CIITA antibody, C2ta antibody, EG669998 antibody, Gm9475 antibody, C2TA antibody, CIITAIV antibody, MHC2TA antibody, NLRA antibody, Mhc2ta antibody, class II, major histocompatibility complex, transactivator antibody, class II major histocompatibility complex transactivator antibody, MHC class II transactivator antibody, class II transactivator antibody, CIITA antibody, LOC710761 antibody, ciita antibody, LOC100443575 antibody, Ciita antibody, LOC100736732 antibody
- 背景
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Anti-CIITA antibody detects CIITA. The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes. CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes. Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression. Antigen can be obtained from Raji cell lysates. Typically levels of CIITA expression are too low to detect endogenous levels of protein expression. Transiently transfected cells are usually employed to study this transcription factor.
Synonyms: MHC class II transactivator CIITA MHC2TA - 基因ID
- 4261
- UniProt
- P33076
- 途径
- Cancer Immune Checkpoints
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