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SF3B3 抗体 (Middle Region)

SF3B3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779034
发货至: 中国
  • 抗原 See all SF3B3 抗体
    SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
    抗原表位
    • 11
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 51
    • 29
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠
    宿主
    • 49
    • 2
    • 1
    克隆类型
    • 41
    • 11
    多克隆
    标记
    • 28
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SF3B3 antibody is un-conjugated
    应用范围
    • 32
    • 23
    • 11
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    EHPPLCGRDH LSFRSYYFPV KNVIDGDLCE QFNSMEPNKQ KNVSEELDRT
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against SF3B3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SF3B3
    Top Product
    Discover our top product SF3B3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1217 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
    别名
    SF3B3 (SF3B3 产品)
    别名
    GB11574 antibody, rse1 antibody, sap130 antibody, sf3b130 antibody, staf130 antibody, sf3b3 antibody, 1810061H24Rik antibody, 5730409A01Rik antibody, AA409318 antibody, D8Ertd633e antibody, RSE1 antibody, SAP130 antibody, mKIAA0017 antibody, ik:tdsubc_2b2 antibody, wu:fb81f05 antibody, xx:tdsubc_2b2 antibody, zgc:55440 antibody, SF3b130 antibody, STAF130 antibody, splicing factor 3b subunit 3 antibody, splicing factor 3B subunit 3 antibody, splicing factor 3b, subunit 3, 130kDa antibody, splicing factor 3b subunit 3 L homeolog antibody, splicing factor 3b, subunit 3 antibody, SF3B3 antibody, LOC550935 antibody, sf3b3 antibody, Sf3b3 antibody, LOC100178056 antibody, sf3b3.L antibody
    背景
    SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: KIAA0017, RSE1, SAP130, SF3b130, STAF130
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, NUDCD3, LGR4, SUMO1, NEDD8, MDM2, RPA3, RPA2, RPA1, ERG, SUZ12, EED, RNF2, EZH2, PRPF40A, WWOX, APBB1, WBP4, TCERG1, FBXO6, CUL1, CUL2, CUL3, CUL4A, SKP2, SKP1, CD81, IGSF8, RBM6, EFTUD2, WHSC1, IFIT3, HSP90AA1, HSPB1, EPS8, TOE1,
    Protein Size: 1217
    分子量
    135 kDa
    基因ID
    23450
    NCBI登录号
    NM_012426, NP_036558
    UniProt
    Q15393
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