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SF3B3 产品

(Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008].

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Featured SF3B3 Categories

SF3B3 抗体

High quality antibodies with extensive validation data.

SF3B3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

SF3B3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SF3B3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7270544
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6147668
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7010966
Quantity 60 μL
Datasheet Datasheet

Recommended SF3B3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959692
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674722
Quantity 96 tests
Datasheet Datasheet

Recommended SF3B3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1319715
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095320
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3136874
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SF3B3 Products

Xie, Guo, Wang, Xu, Zhang, Yu, Liu, Li, Zhao, Zhao, Ye, Liu: "Human albumin attenuates excessive innate immunity via inhibition of microglial Mincle/Syk signaling in subarachnoid hemorrhage." in: Brain, behavior, and immunity, Vol. 60, pp. 346-360, (2016) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Brand, Moggs, Oulad-Abdelghani, Lejeune, Dilworth, Stevenin, Almouzni, Tora: "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation." in: The EMBO journal, Vol. 20, Issue 12, pp. 3187-96, (2001) (PubMed).

Das, Xia, Palandjian, Gozani, Chyung, Reed: "Characterization of a protein complex containing spliceosomal proteins SAPs 49, 130, 145, and 155." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6796-802, (2000) (PubMed).

Synonyms and alternative names related to SF3B3

splicing factor 3b subunit 3 (SF3B3), splicing factor 3B subunit 3 (LOC550935), splicing factor 3b subunit 3 (sf3b3), splicing factor 3b, subunit 3, 130kDa (Sf3b3), splicing factor 3B subunit 3 (LOC100178056), splicing factor 3b subunit 3 L homeolog (sf3b3.L), splicing factor 3b, subunit 3 (Sf3b3), splicing factor 3b, subunit 3 (sf3b3), 1810061H24Rik, 5730409A01Rik, AA409318, D8Ertd633e, GB11574, ik:tdsubc_2b2, mKIAA0017, rse1, RSE1, sap130, SAP130, sf3b3, sf3b130, SF3b130, staf130, STAF130, wu:fb81f05, xx:tdsubc_2b2, zgc:55440

Protein level used designations for SF3B3

  • splicing factor 3b, subunit 3, 130kDa
  • splicing factor 3b, subunit 3
  • splicing factor 3B subunit 3
  • SAP 130
  • SF3b130
  • spliceosome-associated protein 130
  • pre-mRNA-splicing factor SF3b 130 kDa subunit
  • splicing factor 3B subunit 3-like
  • pre-mRNA splicing factor SF3b, 130 kDa subunit
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